abstract：:This article examines how to assess the reliability of potential techniques for performing optimization of biventricular pacemakers in patients with atrial fibrillation. It explores the magnitude of improvement that is likely to be obtained with the optimization of biventricular pacing in this clinical setting and dis...

journal_title：Heart failure clinics

authors： Whinnett ZI,Francis DP

更新日期：2013-10-01 00:00:00

abstract：:The detrimental pathophysiology of heart failure (HF) leaves room for physiologic and metabolomic concepts that include supplementation of micronutrients and macronutrients in these patients. Hence myocardial energetics and nutrient metabolism may represent relevant treatment targets in HF. This review focuses on the ...

journal_title：Heart failure clinics

authors： Trippel TD,Anker SD,von Haehling S

更新日期：2013-07-01 00:00:00

abstract：:Stress cardiomyopathy is a form of reversible systolic dysfunction of the mid and apical left ventricle with pathologic changes of the electrocardiogram in the absence of an obstructive coronary artery disease. The prevalence of stress cardiomyopathy among patients with symptoms suggestive of myocardial infarction is ...

journal_title：Heart failure clinics

authors： Szardien S,Möllmann H,Willmer M,Akashi YJ,Hamm CW,Nef HM

更新日期：2013-04-01 00:00:00

abstract：:Epidemiologic evidence indicates that abnormal elevations in glycemia and lipidemia after a meal, termed postprandial dysmetabolism, are linked with increased risk of morbidity and mortality due to cardiovascular disease in individuals with or without type 2 diabetes. Both postprandial hyperglycemia and postprandial h...

journal_title：Heart failure clinics

authors： Garber AJ

更新日期：2012-10-01 00:00:00

abstract：:Despite the advances in diagnostic and treatment strategies, and contemporary survival estimates suggesting improved outcomes, the prognosis of patients with pulmonary arterial hypertension (PAH) remains poor. To date, there is no consensus on which prognostic variables or risk prediction strategies best predict survi...

journal_title：Heart failure clinics

authors： Agarwal R,Gomberg-Maitland M

更新日期：2012-07-01 00:00:00

abstract：:This article discusses currently available radionuclide techniques in the diagnostic and prognostic evaluation of patients with chronic heart failure, with a focus on stage B/asymptomatic left ventricular dysfunction. Radionuclide imaging is promising for such patients because it can simultaneously determine left vent...

journal_title：Heart failure clinics

authors： Janardhanan R,Beller GA

更新日期：2012-04-01 00:00:00

abstract：:Oxidative stress represents a persistent imbalance between the production and the compensation of reactive oxygen species. Though predominantly found in advanced heart failure, the most frequent "at-risk" condition has been associated with underlying oxidative stress. It is therefore conceivable that timely detection ...

journal_title：Heart failure clinics

authors： Bhimaraj A,Tang WH

更新日期：2012-01-01 00:00:00

abstract：:With the aging of the population and advances in acute treatment of ischemic events and surgical techniques for coronary artery and valvular heart disease, the prevalence of heart failure has been increasing. Lifestyle modifications are an integral part of preventing and treating most pathologic human conditions, and ...

journal_title：Heart failure clinics

authors： Piña IL,Oghlakian G,Boxer R

更新日期：2011-10-01 00:00:00

abstract：:Transparency is the foundation on which all of research integrity rests. The public trust from patients, providers, and policy makers depends on fidelity to the mandates of accountability and access. Two important foundational practices for maintaining transparency in research and the reporting of clinical trials disc...

journal_title：Heart failure clinics

authors： Bonita RE,Adams S,Whellan DJ

更新日期：2011-10-01 00:00:00

abstract：:Amyloidotic cardiomyopathy (ACMP) occurs in the setting of rare genetic diseases, blood dyscrasias, chronic infection and inflammation, and advanced age. Cardiologists are on the front lines of diagnosis of ACMP when evaluating patients with unexplained dyspnea, congestive heart failure, or arrhythmias. Noninvasive de...

journal_title：Heart failure clinics

authors： Seldin DC,Berk JL,Sam F,Sanchorawala V

更新日期：2011-07-01 00:00:00

abstract：:Implanted devices in heart failure patients improve survival, but requires correct prescription, programming, and monitoring. Requirements change since heart failure is a dynamic condition. Repeated episodes of acute decompensation increase mortality. Events involve several processes converging to manifest with fluid ...

journal_title：Heart failure clinics

authors： Varma N,Wilkoff B

更新日期：2011-04-01 00:00:00

abstract：:Depression is an all too common occurrence in heart failure patients. Depressive symptoms, however, sometimes are confused with the physical repercussions of heart failure. This article highlights different screening assessments for major depression and recommends treatment for this population. ...

journal_title：Heart failure clinics

authors： Saveanu RV,Mayes T

更新日期：2011-01-01 00:00:00

abstract：:Since the sentinel discovery of long QT syndrome as a channelopathy in 1995, many significant strides have been made related to exposing the pathogenic mechanisms underlying sudden cardiac death. However, elucidating the most influential genetic and environmental determinants that underlie the variable penetrance and ...

journal_title：Heart failure clinics

authors： Vatta M,Ackerman MJ

更新日期：2010-10-01 00:00:00

abstract：:Over the past decade, a growing body of literature has led to a greater understanding of the relationship between anemia and the outcomes in patients with heart failure. This article reviews the current literature on the association between anemia and a broad range of clinical outcomes, including mortality, hospitaliz...

journal_title：Heart failure clinics

authors： Salisbury AC,Kosiborod M

更新日期：2010-07-01 00:00:00

abstract：:The heart failure syndrome is known to represent a final common pathway for a broad range of etiologies, but there is tremendous variation in the propensity to develop congestive heart failure after a given insult. This variation is thought to result in part from inherited differences in myocardial, vascular or system...

journal_title：Heart failure clinics

authors： MacRae CA

更新日期：2010-04-01 00:00:00

abstract：:Hypertension is a common condition that is a well-described risk factor for the development of cerebrovascular disease, myocardial infarction and heart failure. Medical therapy for hypertension may not only prevent development of these potentially devastating illnesses but may be used to treat high blood pressure, whi...

journal_title：Heart failure clinics

authors： Sheppard R

更新日期：2010-01-01 00:00:00

abstract：:Oxidative stress is the relative excess of reactive oxygen species (ROS) versus endogenous defense mechanisms. Abundant evidence has demonstrated the role of ROS, along with reactive nitrogen species (RNS), in the pathophysiology of cardiovascular disease, including heart failure. Many biomarkers of oxidative stress h...

journal_title：Heart failure clinics

authors： Trachtenberg BH,Hare JM

更新日期：2009-10-01 00:00:00

abstract：:Cardiovascular magnetic resonance (CMR) is an accurate, reproducible and well-validated imaging technique for the measurement of left ventricular and right ventricular volumes, function, and mass. In patients who have heart failure, CMR is ideally suited both for the initial assessment of fundamental parameters of car...

journal_title：Heart failure clinics

authors： Grothues F,Braun-Dullaeus R

更新日期：2009-07-01 00:00:00

abstract：:Routine cardiac catheterization provides data on left heart, right heart, systemic and pulmonary arterial pressures, vascular resistances, cardiac output, and ejection fraction. These data are often then applied as markers of cardiac preload, afterload, and global function, although each of these parameters reflects m...

journal_title：Heart failure clinics

authors： Borlaug BA,Kass DA

更新日期：2009-04-01 00:00:00

abstract：:It is widely recognized that the impact of heart failure on society is enormous. The research community has responded, resulting in an ongoing period of rapid advancement across a wide range of fields. The pace of progress is perhaps most apparent in the barrage of new and revised terminology appearing in the heart fa...

journal_title：Heart failure clinics

authors： Green GB

更新日期：2009-01-01 00:00:00

abstract：:With an aging population, the United States health care delivery system is struggling to handle an onslaught of chronic disease burden. The current process of regulatory oversight and pay-for-performance reimbursement is a reality in today's health care delivery system. To maintain profitability, facilities must be wi...

journal_title：Heart failure clinics

authors： Sieck SG,Moseley MG

更新日期：2009-01-01 00:00:00

abstract：:Prostaglandins are products of intracellular arachidonate metabolism via the cyclooxygenase pathways. In the kidney, prostaglandins are modulators of afferent arteriole autoregulation. In diminished effective intravascular volume, vasodilatory prostaglandins reduce afferent arteriolar resistance, helping to maintain o...

journal_title：Heart failure clinics

authors： Akinbamowo AO,Salzberg DJ,Weir MR

更新日期：2008-10-01 00:00:00

abstract：:The myocytes comprising the ventricular mass are arranged so as to function in antagonistic fashion, the walls having the capacity to generate both constrictive and dilatory forces. This dualistic activity is organized on the basis of a site-specific morphologic pattern, permitting marked regional specificity for mura...

journal_title：Heart failure clinics

authors： Lunkenheimer PP,Redmann K,Niederer P,Schmid P,Smerup M,Stypmann J,Däbritz S,Rothaus K,Anderson RH

更新日期：2008-07-01 00:00:00

abstract：:This article reviews the results of observational statin use in clinical trials of patients who have systolic heart failure, in post-myocardial infarction with left ventricular dysfunction, and in cardiac device trials. This article shows a consistent benefit of statins on mortality (approximately 25%) in heart failur...

journal_title：Heart failure clinics

authors： Levy WC

更新日期：2008-04-01 00:00:00

abstract：:Heart failure is defined as the pathologic state in which the heart is unable to pump blood at a rate required by the metabolizing tissues or can do so only with an elevated filling pressure. Heart failure in adults most frequently results from the inability of the left ventricle to fill (diastolic performance) or eje...

journal_title：Heart failure clinics

authors： Fukuta H,Little WC

更新日期：2008-01-01 00:00:00

abstract：:Diuretics are tools of considerable therapeutic importance. First, they effectively reduce blood pressure, while at the same time decreasing the morbidity and mortality associated with hypertension. Diuretics are currently recommended as first-line therapy for the treatment of hypertension. In addition, they remain an...

journal_title：Heart failure clinics

authors： Sica DA,Gehr TW,Frishman WH

更新日期：2007-10-01 00:00:00

abstract：:The authors analyze the question of whether heart transplantation still has a role in the current era of complex technologies. To achieve this objective, the authors first discuss the known benefits of different therapeutic modalities currently available for patients who have end-stage heart failure, including pharmac...

journal_title：Heart failure clinics

authors： Cadeiras M,von Bayern MP,Deng MC

更新日期：2007-07-01 00:00:00

abstract：:The mean age and risk profile of patients referred for cardiac surgery is constantly increasing. Surgeons are now inclined to accept high-risk patients because interventional cardiology provides less invasive alternatives for an overlapping patient cohort. As risk profile increases so does hospital mortality. Patients...

journal_title：Heart failure clinics

authors： Westaby S,Balacumaraswami L,Sayeed R

更新日期：2007-04-01 00:00:00

abstract：:Patient monitoring following heart transplantation aims to detect complications (eg, acute graft rejection, vasculopathy, infection) early and contributes to risk prognostication. Numerous biomarkers of different biologic pathways have been evaluated as ancillary diagnostic and prognostic tools to reduce the need for ...

journal_title：Heart failure clinics

authors： Dengler TJ,Gleissner CA,Klingenberg R,Sack FU,Schnabel PA,Katus HA

更新日期：2007-01-01 00:00:00